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Department of Applied Mathematics and Theoretical Physics

Professor Stephen John Eglen

Career

  • 1997-2000 Wellcome Trust Fellow in Mathematical Biology, Edinburgh
  • 2000-2001 Lecturer, School of Informatics, Edinburgh
  • 2001-2004 Wellcome Trust Travelling Fellowship, St Louis and Edinburgh
  • 2004-2006 Lecturer, DAMTP
  • 2006-2015 Senior Lecturer, DAMTP
  • 2015- Reader. DAMTP

Research

Stephen Eglen is a computational neuroscientist: he uses computational methods to study the development of the nervous system, using mostly the retina and other parts of the visual pathway as a model system. He is particularly interested in questions of structural and functional development:

Structural development: how do retinal neurons acquire their positional information within a circuit?

Functional development: what are the mechanisms by which neurons make contact with each other, to perform functioning circuits?

Selected Publications

Please see my publications page

Publications

Can Retinal Ganglion Cell Dipoles Seed Iso-Orientation Domains in the Visual Cortex?
M Schottdorf, SJ Eglen, F Wolf, W Keil
– PloS one
(2014)
9,
e86139
(doi: 10.1371/journal.pone.0086139)
Retinotopic Development, Models of
SJ Eglen
(2014)
1
(doi: 10.1007/978-1-4614-7320-6_406-1)
Following the ontogeny of retinal waves: pan‐retinal recordings of population dynamics in the neonatal mouse
A Maccione, MH Hennig, M Gandolfo, O Muthmann, J van Coppenhagen, SJ Eglen, L Berdondini, E Sernagor
– The Journal of Physiology
(2013)
592,
1545
(doi: 10.1113/jphysiol.2013.262840)
A data repository and analysis framework for spontaneous neural activity recordings in developing retina
SJ Eglen, M Weeks, M Jessop, J Simonotto, T Jackson, E Sernagor
(2013)
(doi: 10.1101/000455)
Neural circuits for peristaltic wave propagation in crawling drosophila larvae: Analysis and modeling
J Gjorgjieva, J Berni, JF Evers, SJ Eglen
– Frontiers in Computational Neuroscience
(2013)
7,
24
(doi: 10.3389/fncom.2013.00024)
Following the assembly of functional circuitry: high resolution large-scale population neuronal dynamics in the neonatal mouse retina
A Maccione, MH Hennig, M Gandolfo, O Muthmann, M Down, CJ van, A Jones, SJ Eglen, L Berdondini, E Sernagor
(2013)
Parasol cell mosaics are unlikely to drive the formation of structured orientation maps in primary visual cortex.
VRA Hore, JB Troy, SJ Eglen
– Vis Neurosci
(2012)
29,
283
(doi: 10.1017/s0952523812000338)
GABAergic control of retinal ganglion cell dendritic development.
FP Chabrol, SJ Eglen, E Sernagor
– Neuroscience
(2012)
227,
30
(doi: 10.1016/j.neuroscience.2012.09.040)
Compensatory redistribution of neuroligins and N-cadherin following deletion of synaptic β1-integrin.
PW Keeley, B Sliff, SC Lee, PG Fuerst, RW Burgess, SJ Eglen, BE Reese
– The Journal of Comparative Neurology
(2012)
520,
1349
(doi: 10.1002/cne.23033)
Neuronal clustering and fasciculation phenotype in Dscam- and Bax-deficient mouse retinas.
PW Keeley, BJ Sliff, SC Lee, PG Fuerst, RW Burgess, SJ Eglen, BE Reese
– The Journal of Comparative Neurology
(2012)
520,
Spc1
(doi: 10.1002/cne.23089)
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Research Group

Computational Biology

Email

S.J.Eglen@damtp.cam.ac.uk

Room

G0.11

Personal homepage

http://www.damtp.cam.ac.uk/user/sje30/

Study at Cambridge

About the University

Research at Cambridge