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Department of Applied Mathematics and Theoretical Physics

Career

  • 1997-2000 Wellcome Trust Fellow in Mathematical Biology, Edinburgh
  • 2000-2001 Lecturer, School of Informatics, Edinburgh
  • 2001-2004 Wellcome Trust Travelling Fellowship, St Louis and Edinburgh
  • 2004-2006 Lecturer, DAMTP
  • 2006-2015 Senior Lecturer, DAMTP
  • 2015- Reader. DAMTP

Research

Stephen Eglen is a computational neuroscientist: he uses computational methods to study the development of the nervous system, using mostly the retina and other parts of the visual pathway as a model system. He is particularly interested in questions of structural and functional development:

Structural development: how do retinal neurons acquire their positional information within a circuit?

Functional development: what are the mechanisms by which neurons make contact with each other, to perform functioning circuits?

Selected Publications

Please see my publications page

Publications

Retinal development
E Sernagor, S Eglen, B Harris, R Wong
(2006)
1
Automated feature extraction for the classification of human in vivo13C NMR spectra using statistical pattern recognition and wavelets
AR Tate, D Watson, S Eglen, TN Arvanitis, EL Thomas, JD Bell
– Magnetic Resonance in Medicine
(2005)
35,
834
LL5β
M Kishi, TT Kummer, SJ Eglen, JR Sanes
– J Cell Biol
(2005)
169,
355
Mapping by waves: Patterned spontaneous activity regulates retinotopic map refinement
SJ Eglen, J Demas, ROL Wong
– Neuron
(2003)
40,
1053
Dopaminergic amacrine cells in the inner nuclear layer and ganglion cell layer comprise a single functional retinal mosaic.
SJ Eglen, MA Raven, E Tamrazian, BE Reese
– J Comp Neurol
(2003)
466,
343
Developmental Modulation of Retinal Wave Dynamics: Shedding Light on the GABA Saga
E Sernagor, C Young, SJ Eglen
– J Neurosci
(2003)
23,
7621
Segregation of ON and OFF Retinogeniculate Connectivity Directed by
Christopher W. Lee, Christopher W, Stephen J. Eglen, Rachel O. L. Wong
(2003)
Determinants of the exclusion zone in dopaminergic amacrine cell mosaics.
MA Raven, SJ Eglen, JJ Ohab, BE Reese
– The Journal of Comparative Neurology
(2003)
461,
123
Developmental loss of synchronous spontaneous activity in the mouse retina is independent of visual experience.
J Demas, SJ Eglen, ROL Wong
– J Neurosci
(2003)
23,
2851
Influence of cell fate mechanisms upon retinal mosaic formation: A modelling study
SJ Eglen, DJ Willshaw
– Development (Cambridge, England)
(2002)
129,
5399
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Research Group

Computational Biology

Room

G0.11